Evaluation of multimodal imaging in carriers of X-linked retinitis pigmentosa
نویسندگان
چکیده
منابع مشابه
X-linked retinitis pigmentosa.
Of 107 consecutive patients with genetically-determined retinitis pigmentosa, 23 were provisionally diagnosed as having inherited the disease in an X-linked fashion. 42 affected males and 61 females were examined, and from the data obtained the following conclusions were drawn: (1) X-linked retinitis pigmentosa exists and is distinct from choroideremia. (2) In contrast to the results of previou...
متن کاملOrigin of tapetal-like reflexes in carriers of X-linked retinitis pigmentosa.
PURPOSE To determine the origin of the tapetal-like reflex (TLR) in carriers of X-linked retinitis pigmentosa. METHODS Spectral fundus reflectance of carriers of X-linked retinitis pigmentosa was measured and compared with that of normal subjects. The influence of visual pigment was determined by measuring the density difference, that is, the difference between the logarithmically scaled spec...
متن کاملElectroretinographic testing as an aid in detection of carriers of X-chromosome-linked retinitis pigmentosa.
Twenty-two of 23 obligate female carriers in nine families with known X-chromosome-linked retinitis pigmentosa were detected on the basis of abnormal full-field electroretinograms (ERGs). Only 14 of these carriers had fundus findings characteristic of the carrier state. Electroretinograms of carriers were either reduced in amplitude to white light under dark-adapted conditions or delayed in con...
متن کاملImage analysis of the tapetal-like reflex in carriers of X-linked retinitis pigmentosa.
PURPOSE To increase understanding of the tapetal-like reflex (TLR), a unique retinal feature in carriers of X-linked retinitis pigmentosa (XLRP). METHODS Color fundus photographs of XLRP carriers were digitized at high resolution. A mathematical model of the imaging system was used to restore the digital retinal images. TLR was separated from the retinal background with an automated segmentat...
متن کاملGene Therapy for X-Linked Retinitis Pigmentosa
Copyright: © 2013 Shu X. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Retinitis Pigmentosa (RP) is a group of heterogeneous genetic disorders with a worldwide prevalence of 1 in 4000 individuals [1]. RP can...
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ژورنال
عنوان ژورنال: Experimental Eye Research
سال: 2013
ISSN: 0014-4835
DOI: 10.1016/j.exer.2013.05.003